Feng-Qian Li, PhD (Associate Professor of Research)

Siller, S. S., Burke, C. M., Li, F.-Q., & Takemaru, K.-I. (2015)
Chibby functions to preserve normal ciliary morphology through the regulation of intraflagellar transport in airway ciliated cells.
Cell Cycle. Aug 12:0. PMID: 26266958

Li, F.-Q., Siller, S. S., & Takemaru, K.-I. (2015).
Basal body docking in airway ciliated cells. Oncotarget, Vol. 6, No. 24

Burke, M.C., Li, F.-Q., Cyge, B., Arashiro, T., Brechbuhl, H. M., Chen X. W., Siller, S. S., Weiss M. A., O’Connell C. B., Love, D., Westlake C. J., Reynolds, S. D., Kuriyama. R. & Takemaru, K.-I. (2014)
Chibby promotes ciliary vesicle formation and basal body docking during airway cell differentiation.
J. Cell Biol., 207 (1), 123-137 PMCID: PMC4195830
• Featured on Journal Cover and highlighted in “In This Issue”.

Lee, Y.-L., Sante, J., Comerci C. J., Cyge, B., Menezes L. F., Li, F.-Q., Germino G. G., Moernerr W. E.,  Takemaru, K.-I., & Stearns, T. (2014)
Cby1 promotes Ahi1 recruitment to a ring-shaped domain at the centriole-cilium interface and facilitates proper cilium formation and function.
Mol. Biol. Cell, 25(19): 2919-2933. PMCID: PMC4230582

Steere, N,, Chae, V., Burke, M., Li, F.-Q., Takemaru, K.-I., & Kuriyama, R. (2012)
A Wnt/β-catenin pathway antagonist Chibby binds Cenexin at the distal end of mother centrioles and functions in primary cilia formation.
PLoS ONE, 7(7): e41077. PMCID: PMC3401179

Fischer, V., Brown-Grant, D.-A., & Li, F.-Q. (2012)
Chibby suppresses growth of human SW480 colon adenocarcinoma cells through inhibition of β-catenin signaling.
J. Mol. Signal., 31;7(1):6. PMCID: PMC3463480

Takemaru, K.-I.,, Chen, X.W. and & Li, F.-Q. (2012)
β-Catenin.
Encyclopedia of signaling molecules, Springer

Cyge, B., Fischer, V., Takemaru, K.-I., & Li, F.-Q., (2011)
Generation and characterization of monoclonal antibodies against human Chibby protein.
Hybridoma, 30 (2):163-168. PMCID: PMC3133832

Cyge, B., Fischer, V., Takemaru, K.-I., & Li, F.-Q. (2011)
Mouse anti-Chibby monoclonal antibodies (clones 8-2 and 27-11).
Hybridoma. 30 (2) 208. PMID: 21529299

Love, D., Li, F.-Q., Burke, M.C., Cyge, B., Ohmitsu, M., Cabello, M., Larson, J.E., Brody, S.L., Cohen, J.C., & Takemaru, K.-I. (2010)
Altered lung morphogenesis, epithelial cell differentiation and mechanics in mice deficient in the Wnt/β-catenin antagonist Chibby.
PLoS One, 5(10): e13600. doi:10.1371/journal.pone.0013600. PMCID: PMC2963606

*Co-correspondence
*Li, F.-Q., Mofunanya, A., Fischer, V., Hall, J., & *Takemaru, K.-I. (2010)
Nuclear-cytoplasmic shuttling of Chibby regulates subcellular localization and signaling activity of β-catenin.
Mol. Biol. Cell, 21:311-322. PMCID: PMC2808236

Mofunanya, A., Li, F.-Q., Hsieh, J.-C. & Takemaru, K.-I. (2009)
Chibby forms a homodimer through a heptad repeat of leucine residues in its C-terminal coiled-coil motif.  
BMC Mol. Biol., 10:41 doi: 10.1186/1471-2199-10-41. PMCID: PMC2686680

Voronina, V.A., Takemaru, K.-I., Treuting, P.,  Love, D., Grubb, B.R., Hajjar, A.M.,  Adams, A.,  Li, F.-Q., & Moon, R.T. (2009)
Inactivaton of Chibby affects function of motile airway cilia.
J. Cell Biol., 185 (2): 225-233. PMCID: PMC2700371

*Co-correspondence
Takemaru, K.-I., Fischer, V., & Li, F.-Q. (2009)
Fine-tuning of nuclear β-catenin by Chibby and 14-3-3.
Cell Cycle. 8 (2): 8: 210-213. PMCID: PMC2810615
*Li, F.-Q., Mofunanya, A., Harris, K., & *Takemaru, K.-I. (2008)
Chibby cooperates with 14-3-3 to regulate β-catenin subcellular distribution and signaling activity.
J. Cell Biol., 181 (7): 1141-1154. PMCID: PMC2442201
•  Research Highlights in Nature Reviews-Molecular Cell Biology by Kritikou, (2008)- (http://www.nature.com/nrm/journal/v9/n8/full/nrm2462.html), Nat. Rev. Mol. Cell Biol., 9:584.
•  Selected Updates in Nature Signaling Gateway  (2008)-AKTing in Wnt pathway.
•  Faculty of 1000 Cell Biology (2008) by Frans Van Roy

Takemaru, K.-I., Ohmitsu, M, & Li, F.-Q. (2008)
An oncogenic hub: β-catenin as a molecular target for cancer therapeutics.
Handbook Exp. Pharmacology, 186: 261-284. PMID: 18491056

Li, F.-Q., Singh, A.M., Mofunanya, A., Love, D., Terada, N., Moon, R.T., & Takemaru, K.-I. (2007)
Chibby promotes adipocyte differentiation through inhibition of β-catenin signaling.
Mol. Cell Biol., 27 (12): 4347-4354. PMCID: PMC1900052

Singh, A.M., Li, F.-Q., Hamazaki, T., Takemaru, K.-I., & Terada, N. (2007)
Chibby, an antagonist of the Wnt/β-catenin pathway, facilitates cardiomyocyte differentiation of murine embryonic stem cells.
Circulation, 115 (5): 617-626. PMCID: PMC2565513

Benson, K.F., Person, R.E., Li, F.-Q., Williams, K.,  &  Horwitz, M. (2004)
Paradoxical homozygous expression from heterozygotes and heterozygous expression from homozygotes as a consequence of transcriptional infidelity through a polyadenine tract in the AP3B1 gene responsible for canine cyclic neutropenia.
Nucleic. Acids. Res. 32(21): 6327-6333. PMCID: PMC535682

Horwitz, M., Benson, K.F., Duan, Z., Li, F.-Q., & Person R.E. (2004)
Hereditary neutropenia: dogs explain human neutrophil elastase mutations
Trends Mol. Med. 10 (4): 163-170. PMID: 15059607

Li, F.-Q., Person, R.E., Takemaru, K.-I., Williams, K., Meade-White, K., Ozsahin, A.H., Gungor, T., Moon, R.T., & Horwitz, M. (2004)
Lymphoid enhancer factor-1 links two hereditary leukemia syndromes through core-binging factor regulation of ELA2.
J. Biol. Chem. 279 (4): 2873-2884. PMID: 14594802

Duan, Z., Li, F.-Q., Wechsler, J., Meade-White, K., Williams, K., Benson, K.F., & Horwitz, M. (2004)
A novel Notch protein, N2N, targeted by neutrophil elastase and implicated in hereditary neutropenia.  
Mol. Cell Biol. 24 (1): 58-70. PMCID: PMC303357

Benson, K.F., Li, F.-Q., Person, R.E., Albani, D., Duan, Z., Wechsler, J., Meade-White, K., Williams, K., Acland, G.M., Niemeyer, G., Lothrop, C.D., & Horwitz, M. (2003)
Mutations associated with neutropenia in dogs and humans disrupt intracellular transport of neutrophil elastase.  
Nat. Genet. 35(1): 90-96. PMCID: PMC2832179

*Contributed equally
*Person, R.E., * Li, F.-Q., *Duan, Z., Benson, K.F., Wechsler, J., Papadaki, H.A., Eliopoulos, G., Kaufman, C., Bertolone, S.J., Nakamoto, B., Papayannopoulou, T., Grimes, H.L., & Horwitz, M. (2003)
Mutations in proto-oncogene Gfi1 cause human neutropenia and target ELA2.  
Nat. Genet. 34(3): 308-312. PMCID: PMC2832179

Horwitz, M. Benson, K.F., Duan, Z., Person, R.E., Wechsler, J., Williams, K., Albani, D., & Li, F.-Q. (2003)
Role of neutrophil elastase in bone marrow failure syndromes: molecular genetic revival of the chalone hypothesis.
Curr. Opin. Hematol., 10 (1): 49-54. PMID: 12483111

Li, F.-Q., & Horwitz, M. (2001)
Characterization of mutant neutrophil elastase in severe congenital neutropenia.  
J. Biol. Chem., 276 (17): 14230-14241. PMID: 11278653    

Li, F.-Q., Coonrod, A., & Horwitz, M. (2000)
Selection of a dominant negative retinoblastoma protein (RB) inhibiting satellite myoblast differentiation implies an interaction between MyoD and RB.  
Mol. Cell Biol., 20 (14): 5129-5139. PMCID: PMC85962

Takemaru, K.-I., Li, F.-Q., Ueda, H., & Hirose, S. (1997)
Multiprotein bridging factor 1 (MBF1) is an evolutionarily conserved transcriptional coactivator that connects a regulatory factor and TATA element-binding protein.  
Proc. Natl. Acad. Sci. USA, 94 (14): 7251-7256. PMCID: PMC23807

Li, F.-Q., Takemaru, K.-I., Goto, M., Ueda, H., & Hirose, S. (Feb. 1997)
Transcriptional activation through interaction of MBF2 with TFIIA.  
Genes to Cells, 2 (2): 143-153. 143-153. PMID: 9167971

Li, F.-Q., Coonrod, A., & Horwitz, M. (1996).
Preferential MyoD homodimer formation demonstrated by a general method of dominant negative mutation employing fusion with a lysosomal protease.  
J. Cell Biol., 135 (4): 1043-1057. PMCID: PMC2133387

Li, F.-Q., Ueda, H., & Hirose, S. (1994).
Mediators of activation of fushi tarazu gene transcription by BmFTZ-F1.  
Mol. Cell. Biol., 14 (5): 3013-3021. PMCID: PMC358669.