Faculty / Research

Signaling

Leveraging microfluidics and optogenetics to elucidate molecular mechanisms of spindle orientation, ciliogenesis, polarity, actin cortex formation and axonogenesis.
Extracellular matrix in the brain: roles during development and during neurodegeneration
Lipid Signaling: Roles in mitochondrial biology, spermatogenesis, diabetes, immune function, the CNS, platelet activation, and cancer; - Imaging Pancreatic β-cells using metabolomics and MRI.
Signal Transduction in Differentiation and Development: Roles of Molecular Scaffold Molecules (e.g., AKAPs and Dishevelleds)
Molecular Mechanism of Protein Kinase and Ubiquitin Ligase signaling in Cancer and Aging
Cell Signaling and Ciliogenesis in Mammalian Development, Health and Disease
Genetically modified mouse models of neuropsychiatric diseases: how does signaling by axonal NRG1 proteins regulate the development, maturation and plasticity of key cortical – limbic circuits.
Neuro-immune interactions: Cross-talk between the nervous and immune systems in health and disease